The goal of treatment for hemophilia A is to replace the missing clotting factor (factor VIII) in order to stop and prevent bleeding.1

Treatment for Moderate and Severe Hemophilia A*1,2

The main treatment for moderate and severe hemophilia A is factor VIII replacement therapy. There are two types of factor VIII products: human plasma-derived factor VIII and recombinant factor VIII. Both of these options are effective and a healthcare provider can help the patient decide which option is best.

Factor VIII replacement therapy involves infusing the missing clotting factor directly into the bloodstream. Factor VIII infusions may be given1:

  • As needed to stop bleeding when it occurs (on-demand therapy)
  • On a regular basis to prevent bleeding (prophylactic therapy)

*Mild hemophilia may be treated with an injection of desmopressin. Desmopressin stimulates factor VIII production in people whose bodies can still make some factor VIII.2


References: 1. Dargaud Y, Negrier C. Haemophilia therapies. Expert Opin Biol Ther. 2007;7:651–663. 2. National Hemophilia Foundation. MASAC recommendation #187. MASAC recommendations concerning the treatment of hemophilia and other bleeding disorders. Accessed January 28, 2009.